グループ討論

Interactive Breakout Discussions are informal, moderated discussions, allowing participants to exchange ideas and experiences and develop future collaborations around a focused topic. Each discussion will be led by a facilitator who keeps the discussion on track and the group engaged. To get the most out of this format, please come prepared to share examples from your work, be a part of a collective, problem-solving session, and participate in active idea sharing.

2024年4月25日（木） 12:05 - 13:05

Breakout Discussions with Hosted Luncheon

TOPIC: Optimizing Cell Therapy: Antigen Selection, Sequence and Targeting Strategies
Moderator: Sebastian Kobold, MD, Professor, Clinical Pharmacology, Klinikum der Universitat Munchen

How can we pick the best antigens for targeting?
How many antigens and in which sequence do we need?
What would the properties of ideal adaptors or modules for cell therapy look like?
Will targeting be enough?

TOPIC: Engineering Strategies for Next-Generation CAR T Cells
Moderator: Michael Traxlmayr, PhD, Group leader, CD Laboratory for Next-Generation CAR T Cells, University of Natural Resources & Life Sciences

Logic gated CAR T cells
Small molecule-regulated switches to control CAR T cell function
Improving efficacy, while maintaining safety

TOPIC: Optimizing Engineering of Bi and Multi-specific Antibodies
Moderator: Hikaru Koga, MS, Research Scientist, Biologics R&D, Chugai Pharmaceutical Co. Ltd.

Optimizing binding affinity
Mitigating off-target effects
Improving stability
Engineering for optimal manufacturability and scalability
Leveraging computational tools

TOPIC: Bi and Multi-Specific Antibody Discovery and Emerging Formats
Moderator: Ruud de Wildt, PhD, Vice President, Pipeline Delivery, T-Therapeutics