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Generative AI
生成AI

Harness Data Potential to Drive Innovation and Advance Biomedical Research
データのポテンシャルを活用してイノベーションを推進し、バイオメディカル研究を前進

2025年4月2日〜4日 米国東部標準時(EDT)

データ量が拡大し続ける中、バイオファーマ組織はイノベーションを推進し、実用的なインサイトを得るための比類ない機会に恵まれています。このような急成長にもかかわらず、従来のデータ分析・共有方法では追いつくことができず、組織は断片的なデータソース、一貫性のないフォーマット、データの全体像を妨げる時代遅れのシステムに悩まされています。生成AIは、変革の力として登場し、これらの課題を克服することで、ライフサイエンスの研究開発を再定義することを約束しています。ブレークスルーの加速からデータドリブン戦略の最適化、複雑なプロセスの自動化まで、生成AIは大きな可能性を秘めています。ただし、倫理的・規制的な状況を乗り超えながら、AIによって生成されたデータの正確性と信頼性を確保することは、依然として重要です。「生成AI」トラックでは、これらの極めて重要な側面を探求し、導入の障壁、進化するデータ戦略とプラットフォーム、実際のユースケースと将来の予測を紹介します。生成AIを活用して研究開発の新たな局面を切り開き、ライフサイエンスに対する統合的かつ革新的なアプローチへの道を開く方法を発見するために、ぜひご参加ください。

4月2日(水)

Registration Open8:00 am

Recommended Pre-Conference Workshops and Symposia*9:00 am

On Wednesday, April 2, 2025, Cambridge Healthtech Institute is pleased to offer five pre-conference Workshops scheduled across two time slots (9:00 am–12:00 pm and 1:15–4:15 pm) and three Symposia from 9:00 am–4:20 pm. All are designed to be instructional, interactive, and provide in-depth information on a specific topic. They allow for one-on-one interaction and provide a great way to explain more technical aspects that would otherwise not be covered during the main conference tracks that take place Thursday–Friday.

*Separate registration required. See details on the Symposia here and details on the Workshops here.

4:40 pm

Organizer's Remarks

Cindy Crowninshield, Executive Event Director, Cambridge Healthtech Institute

4:45 pm Talk Title to be Announced

Speaker to be Announced, CLOVERTEX

4:55 pm PLENARY KEYNOTE PRESENTATION:

From Bytes to Breakthroughs: Generative AI Driving the Future of Life Sciences and Healthcare

Sofia Guerra, Vice President, Bessemer Venture Partners

Subha Madhaven, Vice President and Head, AI/ML, Quantitative and Digital Sciences, Global Metrics and Data Management, Pfizer Inc.

Generative AI has the potential to transform life sciences and deliver unprecedented insights, automation, and efficiency. But is it? This keynote panel brings together leaders from biopharma, healthcare, and emerging tech who are leveraging AI to advance drug discovery, diagnostics, and patient care. Panelists will share their own case studies and real-world applications and discuss how they’ve tackled challenges—both technical and cultural. Look beyond the hype curve to see how this technology is really being used now and where the next opportunities lie.

Welcome Reception in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)6:10 pm

The Bio-IT Kickoff Reception is a reunion—reconnect with friends, explore cutting-edge research, and celebrate innovation! Enjoy poster presentations, networking, and vote for the Best of Show and Poster awards.

Close of Day7:25 pm

4月3日(木)

Registration Open7:00 am

8:00 am

Organizer's Remarks

Allison Proffitt, Editorial Director, Bio-IT World and Clinical Research News

8:05 am Talk Title to be Announced

Speaker to be Announced, Snowflake Computing Inc

AI-POWERED PLATFORMS IN DRUG DISCOVERY: TACKLING ANTIBIOTIC RESISTANCE AND AGING THERAPEUTICS
創薬におけるAI活用のプラットフォーム:抗生剤耐性と老化治療への取り組み

8:15 am PLENARY KEYNOTE PRESENTATION:

Deep Learning for Antibiotic Discovery

James J. Collins, PhD, Termeer Professor, Medical Engineering & Science, Massachusetts Institute of Technology

In this presentation, we highlight the Antibiotics-AI Project, which is a multi-disciplinary, innovative research program that is leveraging MIT's strengths in artificial intelligence, bioengineering, and the life sciences to discover and design novel classes of antibiotics. The Antibiotics-AI Project is focused on developing, integrating, and implementing deep learning models and chemogenomic screening approaches: (1) to predict novel antibiotics from expansive chemical libraries with diverse properties, (2) to design de novo novel antibiotics based on learned structural and functional properties of existing and newly discovered antibiotics, and (3) to identify, using explainable deep learning models, the chemical structures and molecular mechanisms underlying the newly discovered and/or designed antibiotics. With these deep learning approaches, we are utilizing multi-scale computation to embrace and harness the complexity of biology and chemistry, so as to discover, design, and develop new classes of antibiotics, up through preclinical studies. Our platform has been designed so that it can be utilized and applied in a rapid fashion to emerging and re-emerging bacterial pathogens, including multidrug-resistant (MDR) bacteria and extensively drug-resistant (XDR) bacteria.

8:45 am PLENARY KEYNOTE PRESENTATION:

Generative AI, Aging Research and Robotics as a Platform for Drug Discovery: From Hype to Clinical Efficacy

Alex Zhavoronkov, PhD, Founder & CEO, Insilico Medicine

9:15 amSession Q&A

Coffee Break in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)9:30 am

Start your morning with coffee, connections, and cutting-edge research! Enjoy poster presentations, network in the Exhibit Hall, vote for awards, and a chance at a fabulous raffle prize!

Organizer's Welcome Remarks10:15 am

GENERATIVE AI IN LIFE SCIENCES: TRANSFORMING DOCUMENT GENERATION, MOLECULAR DISCOVERY, AND R&D
ライフサイエンスにおける生成AI:ドキュメント生成・分子発見・R&Dの変革

10:20 am

Chairperson's Remarks

Rishi R. Gupta, PhD, Director, Data Science, Novartis Institutes for Biomedical Research, Inc.

10:25 am

Scaling Clinical Document Generation: Insights on Technical and User Experience Considerations

Irene Pak, Head, AI Data & Analytics, Bristol Myers Squibb Co.

DocGen AI is our innovative clinical document authoring platform, currently expanding to encompass over 60 document types this year. This talk will outline the latest phase of the platform’s evolution, focusing on technical considerations and user experience, particularly regarding the quality of generated sections. We will also present initial metrics on user adoption and productivity improvements.

10:55 am

Harnessing Institutional Knowledge to Accelerate the Discovery of Medicines

Rishi R. Gupta, PhD, Director, Data Science, Novartis Institutes for Biomedical Research, Inc.

This talk explores how Novartis leverages generative AI to harness institutional knowledge for accelerating drug discovery. By integrating data science and AI-driven insights, this approach unearths critical knowledge assets, streamlining research processes and enhancing decision-making. Attendees will gain an understanding of how AI tools facilitate knowledge discovery, reduce time-to-insight, and drive innovation in pharmaceutical research, ultimately advancing the discovery of effective new therapies.

11:25 am

Generative AI for Molecules

Abhishek Pandey, PhD, Global Lead & Principal Research Scientist, Information Research, AbbVie, Inc.

This talk delves into AI-driven approaches for designing and predicting molecular structures, optimizing drug discovery processes, and uncovering novel therapeutic candidates. Attendees will gain insights into generative AI's transformative role in R&D, enhancing precision and efficiency in molecular and pharmaceutical sciences.

11:55 am Talk Title to be Announced

Speaker to be Announced, Certara USA Inc

12:25 pm Talk Title to be Announced

Speaker to be Announced, ServiceNow

Session Break and Transition to Lunch12:55 pm

1:05 pm Talk Title to be Announced

Speaker to be Announced, Snowflake Computing Inc

Refreshment Break in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)1:35 pm

Bio-IT's hall is bigger than ever—one break won’t cut it! Enjoy dessert and coffee after lunch, explore booths and posters, vote for awards, and participate in our raffle for a chance to win a prize!

STRATEGIC AI INTEGRATION AND GOVERNANCE IN PHARMA
製薬における戦略的AI統合とガバナンス

Chairperson's Remarks (Sponsorship Opportunity Available)2:25 pm

2:30 pm

AI Transformation Unleashed: From Concept to Reality—A Pharma Blueprint

Murtaza Cherawala, Senior Director, IT Data Management, Analytics and Artificial Intelligence, Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, a leader in RNAi-based medicines, leverages GenAI to drive innovation and accelerate the development of groundbreaking therapies. By strategically integrating GenAI across functions, Alnylam bolsters its core capabilities and strategically positions itself to harness AI as a force multiplier. Gain an understanding and insights on Alnylam's successful AI journey from aligning executives around AI goals, establishing governance, identifying and prioritizing high-impact use cases, developing and deploying a comprehensive AI roadmap. You will acquire actionable insights and strategies to initiate and drive Enterprise AI initiatives within your organization, positioning it at the vanguard of technological advancements in the industry.

3:00 pm

Know Your Audits: Using LLMs to Mitigate Risk and Enhance Pharma Supply Chain and Manufacturing Resilience

Achal Dixit, Data Scientist III, Innovation & Digital Health, Bristol Myers Squibb India

This talk introduces a framework approach which explores leveraging GenAI and LLMs to identify key risk factors for large-scale pharmaceutical manufacturers. By correlating insights from both internal and external audit data, the framework enhances competitive intelligence and strengthens supply chain risk mitigation, improving manufacturing site resilience. The use of LLMs enables rapid, scalable analysis that outperforms traditional methods, offering significant cost and time savings through their ability to efficiently parse vast data volumes and improved vectorization.

3:30 pm

Revolutionizing Drug Discovery with Generative AI

Petrina Kamya, PhD, Global Head of AI Platforms & Vice President, Insilico Medicine; President, Insilico Medicine Canada

The traditional drug discovery process is lengthy, costly, and fraught with failure, with development often taking over a decade and costing billions. This talk will explore how generative AI is transforming this paradigm through Insilico Medicine’s innovative machine learning platform, enabling novel target identification, small molecule design, and clinical trial prediction. Discover how generative AI is accelerating drug development and reshaping the future of medicine.

Presentation to be Announced (Sponsorship Opportunity Available)4:00 pm

Best of Show Awards Reception in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)4:30 pm

Unwind with colleagues at our lively reception! Explore posters, vote for the best, network with exhibitors, enjoy a drink, and try to win a raffle prize. Celebrate Best of Show winners!

Close of Day5:45 pm

4月4日(金)

Registration Open7:00 am

Quick Bytes & Networking Breakfast—Lifted Rooftop Restaurant & Bar (Sponsorship Opportunity Available)7:00 am

Start your morning with ‘Quick Bytes & Networking’! Enjoy a cozy restaurant-style setting, quick bites, and speed networking. Connect, converse, and energize your Bio-IT experience before the plenary keynote!

8:00 am

Organizer's Remarks

Cindy Crowninshield, Executive Event Director, Cambridge Healthtech Institute

8:05 am

Innovative Practices Awards: Excellence in Technological Innovation

Allison Proffitt, Editorial Director, Bio-IT World and Clinical Research News

The Innovative Practices Awards recognizes and celebrates technology innovation in the life sciences. Bio-IT World is currently accepting entries for the 2025 Innovative Practices Awards, a competition designed to recognize partnerships and projects pushing our industry forward. Winners will be announced in mid-March 2025, recognized during the Friday, April 4 Plenary Keynote Program, and scheduled to give a podium presentation about their project during the conference. For more details about the Awards and to submit an application, visit www.bioitworldexpo.com/innovativepractices.

8:20 am Talk Title to be Announced

Speaker to be Announced, Illumina

ADVANCING DRUG DISCOVERY AND HEALTHCARE THROUGH DATA-DRIVEN INNOVATION: FROM GENOMICS TO THERAPEUTICS
データドリブンのイノベーションによる創薬とヘルスケアの進歩:ゲノミクスから治療まで

8:30 am PLENARY KEYNOTE PRESENTATION:

Scaling Genomic Medicine: Transforming Newborn Screening through Informatics and Innovation

Robert C. Green, MD, MPH, Professor and Director of Genomes2People Research, Mass General Brigham, Broad Institute, Ariadne Labs and Harvard Medical School

The BabySeq Project has pioneered the integration of genomic sequencing into newborn and childhood screening, uncovering unexpected risk variants and transforming healthcare delivery. This keynote explores the groundbreaking progress in genomic medicine, featuring real-world stories of families impacted by these discoveries. Learn about the informatics challenges and innovative solutions required to scale genomic screening for national and global implementation, reshaping the future of precision medicine.

9:00 am PLENARY KEYNOTE PRESENTATION:

Unlocking the Power of Machine Learning and Data-at-Scale to Deliver with Speed the Best Therapeutic Candidates

Justin M. Scheer, PhD, Vice President In Silico Discovery & Head, Molecular Computational Team, Johnson & Johnson Innovative Medicine

The challenges of high costs, lengthy timelines, and significant attrition have prompted our industry to integrate AI/ML into all aspects of the business. This presentation highlights J&J's strategic investments in AI/ML technologies to enhance the drug discovery processes, including molecule design and optimization. By investing in these technologies with a modality agnostic approach, J&J aims to tackle the hardest targets in drug discovery, ultimately increasing the success rate of delivering better molecules faster.

9:30 amSession Q&A

Coffee Break in the Exhibit Hall with Poster Competition Winners Announced (Sponsorship Opportunity Available)9:45 am

Bio-IT is all about connections! Explore booths, award-winning posters, and network with clients, colleagues, and exhibitors. Grab coffee, build relationships, and stay for a chance to win a raffle prize!

Organizer's Remarks10:30 am

ADVANCED DATA CATALOGING FOR ACCELERATED RESEARCH
研究を加速させる先端のデータカタログ

Chairperson's Remarks (Sponsorship Opportunity Available)10:35 am

10:40 am

Automating Cell Therapy Multi-Modal Ontology Construction and Data Cataloging with RAG+ & LLM

Jenny Wei, PhD, Senior Director, R&D Informatics and Technology, Kite Pharma

As a new therapeutic modality, cell therapy presents complex ontologies and meta-data as challenges and opportunities for the informatics community. Traditional SME-led manual curations and data annotations cannot keep up with the multi-modal data generation speed. Automating ontology enrichment with LLM-augmented named entity recognition (NER), and ontology-driven RAG for meta-data cataloging is leading scientists to a much faster data-to-insights journey. Our presentation will introduce methods using existing large language and embedding models to effectively identify relevant information in a large unstructured knowledge base across targeted scientific fields by generating a domain-specific ontology that will both focus and enhance LLM responses during researcher-initiated search.

Presentation to be Announced11:10 am

Presentation to be Announced (Sponsorship Opportunity Available)12:10 pm

Session Break and Transition to Lunch1:10 pm

Luncheon Presentation (Sponsorship Opportunity Available) or Enjoy Lunch on Your Own1:20 pm

Refreshment Break in the Exhibit Hall with Last Chance for Poster Viewing (Sponsorship Opportunity Available)1:50 pm

Feeling tired? Recharge during the final Networking Exhibit Hall break! Visit booths, explore posters, connect with peers, and turn in your Game Cards for a chance to win a raffle prize.

DRIVING AI INNOVATION: BEST PRACTICES FOR IMPLEMENTATION IN BIOPHARMA
AIイノベーションの推進:バイオファーマにおける導入のベストプラクティス

Chairperson's Remarks (Sponsorship Opportunity Available)2:30 pm

2:35 pm

Unlocking AI Potential: Best Practices for Implementation and Management

Vinod Das, Associate Director, Bayer Pharmaceuticals

Petrina Kamya, PhD, Global Head of AI Platforms & Vice President, Insilico Medicine; President, Insilico Medicine Canada

Srivatsan Nagaraja, Founder, Vidya Seva

As AI transforms drug discovery, development, and precision medicine, understanding the business operations behind these advancements is essential. This session will cover critical aspects such as AI tool selection, project scoping, budget management, and prioritization amid evolving regulations. Gain insights from real-world case studies on successful AI deployment, with strategies to navigate regulatory risks while ensuring cost-effectiveness. Join us for a dynamic discussion to harness AI’s full potential in life sciences innovation.

Close of Conference4:05 pm

* 不測の事態により、事前の予告なしにプログラムが変更される場合があります。

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